Preheat oven to 350°F and grease a 9x13-inch baking dish with nonstick spray.

Cook pasta according to package directions to al dente. Drain well and set aside.

In a large skillet over medium-high heat, season ground beef and Italian sausage with salt and pepper, and cook until browned.

Reduce heat to medium, and add onion and mushrooms. Cook until soft, 4-5 minutes. Add garlic and cook 1 minute more.

Add Italian seasoning, diced tomatoes, and tomato sauce. Stir to combine and simmer for 1-2 minutes. Let cool for 10 minutes.

Spread a small amount of sauce over the bottom of the prepared baking dish, then top with cooked pasta.

Sprinkle Italian cheese over the pasta, followed by the remaining sauce.

Cover dish tightly with foil and bake for 45 minutes.

Remove foil and sprinkle Cheddar cheese over the top. Return to oven and bake until cheese is melted and bubbly, 5-10 minutes.